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The genetic backbone of ankylosing spondylitis: how knowledge of genetic susceptibility informs our understanding and management of disease
Ankylosing spondylitis (AS) is a seronegative, chronic inflammatory arthritis with high genetic burden. A strong association with HLA-B27 has long been established, but to date its contribution to disease aetiology remains unresolved. Recent insights through genome wide studies reveal an increasing...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548471/ https://www.ncbi.nlm.nih.gov/pubmed/35939079 http://dx.doi.org/10.1007/s00296-022-05174-5 |