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The genetic backbone of ankylosing spondylitis: how knowledge of genetic susceptibility informs our understanding and management of disease

Ankylosing spondylitis (AS) is a seronegative, chronic inflammatory arthritis with high genetic burden. A strong association with HLA-B27 has long been established, but to date its contribution to disease aetiology remains unresolved. Recent insights through genome wide studies reveal an increasing...

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Detalles Bibliográficos
Autores principales: Kenyon, Marcus, Maguire, Sinead, Rueda Pujol, Anna, O’Shea, Finbar, McManus, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548471/
https://www.ncbi.nlm.nih.gov/pubmed/35939079
http://dx.doi.org/10.1007/s00296-022-05174-5