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Biomarker-driven feedback control of synthetic biology systems for next-generation personalized medicine

Many current clinical therapies for chronic diseases involve administration of drugs using dosage and bioavailability parameters estimated for a generalized population. This standard approach carries the risk of under dosing, which may result in ineffective treatment, or overdosing, which may cause...

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Detalles Bibliográficos
Autores principales: Stefanov, Bozhidar-Adrian, Fussenegger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548536/
https://www.ncbi.nlm.nih.gov/pubmed/36225597
http://dx.doi.org/10.3389/fbioe.2022.986210