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Population pharmacokinetic model of vancomycin in postoperative neurosurgical patients
Objective: Vancomycin is commonly used in postoperative neurosurgical patients for empirical anti-infective treatment due to the low success rate of bacterial culture in cerebrospinal fluid (about 20%) and the high mortality of intracranial infection. At conventional doses, the rate of target achiev...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548544/ https://www.ncbi.nlm.nih.gov/pubmed/36225566 http://dx.doi.org/10.3389/fphar.2022.1005791 |