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Population pharmacokinetic model of vancomycin in postoperative neurosurgical patients

Objective: Vancomycin is commonly used in postoperative neurosurgical patients for empirical anti-infective treatment due to the low success rate of bacterial culture in cerebrospinal fluid (about 20%) and the high mortality of intracranial infection. At conventional doses, the rate of target achiev...

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Detalles Bibliográficos
Autores principales: Wei, Shifeng, Zhang, Dongjie, Zhao, Zhigang, Mei, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548544/
https://www.ncbi.nlm.nih.gov/pubmed/36225566
http://dx.doi.org/10.3389/fphar.2022.1005791