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Case Report: A novel intergenic MIR4299/MIR8070-RET fusion with RET amplification and clinical response to pralsetinib in a lung adenocarcinoma patient

The identification of receptor-tyrosine kinase gene (RET) fusions in lung cancer has become crucial owing to actionable events that predict responsiveness to tyrosine kinase inhibitors (TKIs). However, RET fusions with distinct partner genes respond differently to TKIs. In this case, a 60-year-old m...

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Detalles Bibliográficos
Autores principales: Wang, Sha-Sha, Wang, Fang, Zeng, Zhen, Gao, Fang, Liu, Huan-Huan, Wang, Hui-Na, Hu, Yi, Qin, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548572/
https://www.ncbi.nlm.nih.gov/pubmed/36226049
http://dx.doi.org/10.3389/fonc.2022.929763