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Platelet-derived TGF-β1 is related to portal vein thrombosis in cirrhosis by promoting hypercoagulability and endothelial dysfunction

BACKGROUND: Portal vein thrombosis (PVT) is a serious complication of cirrhosis accompanied by unclear pathogenesis. Transforming growth factor-beta (TGF-β) has been implicated in atherosclerosis and venous thrombosis whereas study regarding its part in PVT is lacking. The aim of this study was to e...

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Detalles Bibliográficos
Autores principales: Jiang, Siyu, Ai, Yingjie, Ni, Liyuan, Wu, Ling, Huang, Xiaoquan, Chen, Shiyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548594/
https://www.ncbi.nlm.nih.gov/pubmed/36225950
http://dx.doi.org/10.3389/fcvm.2022.938397