Analysis of two cooperating antibodies unveils immune pressure imposed on HIV Env to elicit a V3-glycan supersite broadly neutralizing antibody lineage

Elicitation of broadly neutralizing antibodies (bnAbs) is a goal of vaccine design as a strategy for targeting highly divergent strains of HIV-1. Current HIV-1 vaccine design efforts seek to elicit bnAbs by first eliciting their precursors through prime-boost regimens. This requires an understanding...

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Detalles Bibliográficos
Autores principales: Finkelstein, Maxwell T., Parker Miller, Emma, Erdman, Molly C., Fera, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548623/
https://www.ncbi.nlm.nih.gov/pubmed/36225920
http://dx.doi.org/10.3389/fimmu.2022.962939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548623/
https://www.ncbi.nlm.nih.gov/pubmed/36225920
http://dx.doi.org/10.3389/fimmu.2022.962939

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