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Syk promotes phagocytosis by inducing reactive oxygen species generation and suppressing SOCS1 in macrophage-mediated inflammatory responses

OBJECTIVE: Inflammation, a vital innate immune response against infection and injury, is mediated by macrophages. Spleen tyrosine kinase (Syk) regulates inflammatory responses in macrophages; however, its role and underlying mechanisms are uncertain. MATERIALS AND METHODS: In this study, overexpress...

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Detalles Bibliográficos
Autores principales: Yi, Young-Su, Kim, Han Gyung, Kim, Ji Hye, Yang, Woo Seok, Kim, Eunji, Park, Jae Gwang, Aziz, Nur, Parameswaran, Narayanan, Cho, Jae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548688/
https://www.ncbi.nlm.nih.gov/pubmed/36214175
http://dx.doi.org/10.1177/03946320221133018