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Syk promotes phagocytosis by inducing reactive oxygen species generation and suppressing SOCS1 in macrophage-mediated inflammatory responses
OBJECTIVE: Inflammation, a vital innate immune response against infection and injury, is mediated by macrophages. Spleen tyrosine kinase (Syk) regulates inflammatory responses in macrophages; however, its role and underlying mechanisms are uncertain. MATERIALS AND METHODS: In this study, overexpress...
Autores principales: | Yi, Young-Su, Kim, Han Gyung, Kim, Ji Hye, Yang, Woo Seok, Kim, Eunji, Park, Jae Gwang, Aziz, Nur, Parameswaran, Narayanan, Cho, Jae Youl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548688/ https://www.ncbi.nlm.nih.gov/pubmed/36214175 http://dx.doi.org/10.1177/03946320221133018 |
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