Cytoplasmic tail determines the membrane trafficking and localization of SARS-CoV-2 spike protein

The spike (S) glycoprotein of SARS-CoV-2 mediates viral entry through associating with ACE2 on host cells. Intracellular trafficking and palmitoylation of S protein are required for its function. The short cytoplasmic tail of S protein plays a key role in the intracellular trafficking, which contain...

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Detalles Bibliográficos
Autores principales: Li, Qinlin, Liu, Yihan, Zhang, Leiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548995/
https://www.ncbi.nlm.nih.gov/pubmed/36225258
http://dx.doi.org/10.3389/fmolb.2022.1004036