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N6-methyladenosine-related microRNAs risk model trumps the isocitrate dehydrogenase mutation status as a predictive biomarker for the prognosis and immunotherapy in lower grade gliomas

AIM: Lower grade gliomas [LGGs; World Health Organization (WHO) grades 2 and 3], owing to the heterogeneity of their clinical behavior, present a therapeutic challenge to neurosurgeons. The aim of this study was to explore the N6-methyladenosine (m(6)A) modification landscape in the LGGs and to deve...

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Detalles Bibliográficos
Autores principales: Yuan, Feng, Wang, Yingshuai, Cai, Xiangming, Du, Chaonan, Zhu, Junhao, Tang, Chao, Yang, Jin, Ma, Chiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Exploration 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549064/
https://www.ncbi.nlm.nih.gov/pubmed/36226036
http://dx.doi.org/10.37349/etat.2022.00100