Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements

Tetratricopeptide repeat–containing Rab8b-interacting (TRIP8b) protein is a brain-specific subunit of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels, a class of voltage-gated channels modulated by cyclic nucleotides. While the interaction between TRIP8b and the cytosolic C termin...

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Detalles Bibliográficos
Autores principales: Saponaro, Andrea, Vallese, Francesca, Porro, Alessandro, Clarke, Oliver B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549148/
https://www.ncbi.nlm.nih.gov/pubmed/36225302
http://dx.doi.org/10.3389/fphys.2022.998176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549148/
https://www.ncbi.nlm.nih.gov/pubmed/36225302
http://dx.doi.org/10.3389/fphys.2022.998176

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