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Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements

Tetratricopeptide repeat–containing Rab8b-interacting (TRIP8b) protein is a brain-specific subunit of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channels, a class of voltage-gated channels modulated by cyclic nucleotides. While the interaction between TRIP8b and the cytosolic C termin...

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Detalles Bibliográficos
Autores principales:	Saponaro, Andrea, Vallese, Francesca, Porro, Alessandro, Clarke, Oliver B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549148/ https://www.ncbi.nlm.nih.gov/pubmed/36225302 http://dx.doi.org/10.3389/fphys.2022.998176

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