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Mutant p53(K120R) expression enables a partial capacity to modulate metabolism

The TP53 tumor suppressor gene is one of the most studied gene in virtue of its ability to prevent cancer development by regulating apoptosis, cell cycle arrest, DNA repair, autophagy and senescence. Furthermore, the modulation of metabolism by P53 is fundamental for tumor suppressor activity. Studi...

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Detalles Bibliográficos
Autores principales: Monti, Paola, Ravera, Silvia, Speciale, Andrea, Velkova, Irena, Foggetti, Giorgia, Degan, Paolo, Fronza, Gilberto, Menichini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549157/
https://www.ncbi.nlm.nih.gov/pubmed/36226181
http://dx.doi.org/10.3389/fgene.2022.974662