Cargando…
Mutant p53(K120R) expression enables a partial capacity to modulate metabolism
The TP53 tumor suppressor gene is one of the most studied gene in virtue of its ability to prevent cancer development by regulating apoptosis, cell cycle arrest, DNA repair, autophagy and senescence. Furthermore, the modulation of metabolism by P53 is fundamental for tumor suppressor activity. Studi...
Autores principales: | Monti, Paola, Ravera, Silvia, Speciale, Andrea, Velkova, Irena, Foggetti, Giorgia, Degan, Paolo, Fronza, Gilberto, Menichini, Paola |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549157/ https://www.ncbi.nlm.nih.gov/pubmed/36226181 http://dx.doi.org/10.3389/fgene.2022.974662 |
Ejemplares similares
-
Autophagy induced by SAHA affects mutant P53 degradation and cancer cell survival
por: Foggetti, Giorgia, et al.
Publicado: (2019) -
Erratum: Mutant p53K120R expression enables a partial capacity to modulate metabolism
Publicado: (2022) -
TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear
por: Monti, Paola, et al.
Publicado: (2017) -
Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay
por: Monti, Paola, et al.
Publicado: (2021) -
ΔN-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites
por: Monti, Paola, et al.
Publicado: (2014)