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Daily requirement of softgel thyroxine is independent from gastric juice pH

BACKGROUND: Softgel levothyroxine (LT4) preparation showed a better in vitro dissolution profile at increasing pH as compared to tablet LT4 preparation. Clinical studies suggested a better performance of softgel LT4 preparation in patients with gastric disorders but whether this finding is related t...

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Detalles Bibliográficos
Autores principales: Virili, Camilla, Capriello, Silvia, Stramazzo, Ilaria, Brusca, Nunzia, Santaguida, Maria Giulia, Gargano, Lucilla, Bagaglini, Maria Flavia, Bruno, Giovanni, Severi, Carola, Centanni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549358/
https://www.ncbi.nlm.nih.gov/pubmed/36225208
http://dx.doi.org/10.3389/fendo.2022.1002583