A cell-based assay for detection of anti-fibrillarin autoantibodies with performance equivalent to immunoprecipitation

Anti-fibrillarin autoantibodies are useful for the diagnosis and prognosis of systemic sclerosis (SSc). Anti-fibrillarin produces a clumpy nucleolar pattern in indirect immunofluorescence assay on HEp-2 cells (HEp-2 IFA). Here we develop and validate a reliable cell-based anti-fibrillarin assay (Fib...

Descripción completa

Detalles Bibliográficos
Autores principales: Keppeke, Gerson Dierley, Satoh, Minoru, Kayser, Cristiane, Matos, Pedro, Hasegawa, Tomoko, Tanaka, Shin, Diogenes, Larissa, Amaral, Rogerio Quintiliano, Rodrigues, Silvia Helena, Andrade, Luis Eduardo Coelho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549361/
https://www.ncbi.nlm.nih.gov/pubmed/36225928
http://dx.doi.org/10.3389/fimmu.2022.1011110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549361/
https://www.ncbi.nlm.nih.gov/pubmed/36225928
http://dx.doi.org/10.3389/fimmu.2022.1011110

Ejemplares similares