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Metabolic modeling of single bronchoalveolar macrophages reveals regulators of hyperinflammation in COVID-19

SARS-CoV-2 infection induces imbalanced immune response such as hyperinflammation in patients with severe COVID-19. Here, we studied the immunometabolic regulatory mechanisms for the pathogenesis of COVID-19. We depicted the metabolic landscape of immune cells, especially macrophages, from bronchoal...

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Detalles Bibliográficos
Autores principales: Zhao, Qiuchen, Yu, Zhenyang, Zhang, Shengyuan, Shen, Xu-Rui, Yang, Hao, Xu, Yangyang, Liu, Yang, Yang, Lin, Zhang, Qing, Chen, Jiaqi, Lu, Mengmeng, Luo, Fei, Hu, Mingming, Gong, Yan, Xie, Conghua, Zhou, Peng, Wang, Li, Su, Lishan, Zhang, Zheng, Cheng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549388/
https://www.ncbi.nlm.nih.gov/pubmed/36246577
http://dx.doi.org/10.1016/j.isci.2022.105319