Ectopic expression of meiotic cohesin generates chromosome instability in cancer cell line

Many tumors express meiotic genes that could potentially drive somatic chromosome instability. While germline cohesin subunits SMC1B, STAG3, and REC8 are widely expressed in many cancers, messenger RNA and protein for RAD21L subunit are expressed at very low levels. To elucidate the potential of mei...

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Detalles Bibliográficos
Autores principales: Boukaba, Abdelhalim, Liu, Jian, Ward, Carl, Wu, Qiongfang, Arnaoutov, Alexei, Liang, Jierong, Pugacheva, Elena M., Dasso, Mary, Lobanenkov, Victor, Esteban, Miguel, Strunnikov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549395/
https://www.ncbi.nlm.nih.gov/pubmed/36179046
http://dx.doi.org/10.1073/pnas.2204071119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549395/
https://www.ncbi.nlm.nih.gov/pubmed/36179046
http://dx.doi.org/10.1073/pnas.2204071119

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