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Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance

Thymic stromal cells (TSCs) are critical regulators of T cell tolerance, but their basic biology has remained under-characterized because they are relatively rare and difficult to isolate. Recent work has revealed that constitutive autophagy in TSCs is required for self-antigen presentation and cent...

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Detalles Bibliográficos
Autores principales: Semwal, Manpreet K., Hester, Allison K., Xiao, Yangming, Udeaja, Chioma, Cepeda, Sergio, Verschelde, John S., Jones, Nicholas, Wedemeyer, Sarah A., Emtage, Simon, Wimberly, Kymberly, Griffith, Ann V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549397/
https://www.ncbi.nlm.nih.gov/pubmed/36161925
http://dx.doi.org/10.1073/pnas.2204296119