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Redox status regulates autophagy in thymic stromal cells and promotes T cell tolerance
Thymic stromal cells (TSCs) are critical regulators of T cell tolerance, but their basic biology has remained under-characterized because they are relatively rare and difficult to isolate. Recent work has revealed that constitutive autophagy in TSCs is required for self-antigen presentation and cent...
Autores principales: | Semwal, Manpreet K., Hester, Allison K., Xiao, Yangming, Udeaja, Chioma, Cepeda, Sergio, Verschelde, John S., Jones, Nicholas, Wedemeyer, Sarah A., Emtage, Simon, Wimberly, Kymberly, Griffith, Ann V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549397/ https://www.ncbi.nlm.nih.gov/pubmed/36161925 http://dx.doi.org/10.1073/pnas.2204296119 |
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