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Population pharmacokinetics of voriconazole and initial dosage optimization in patients with talaromycosis
The high variability and unpredictability of the plasma concentration of voriconazole (VRC) pose a major challenge for clinical administration. The aim of this study was to develop a population pharmacokinetics (PPK) model of VRC and identify the factors influencing VRC PPK in patients with talaromy...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549404/ https://www.ncbi.nlm.nih.gov/pubmed/36225581 http://dx.doi.org/10.3389/fphar.2022.982981 |