Cargando…

Distinct histological alterations of cortical interneuron types in mouse models of Huntington’s disease

Huntington’s disease (HD) is a debilitating hereditary motor disorder caused by an expansion of the CAG triplet repeat in the Huntingtin gene. HD causes neurodegeneration particularly in the basal ganglia and neocortex. In the cortex, glutamatergic pyramidal neurons are known to be severely affected...

Descripción completa

Detalles Bibliográficos
Autores principales: Voelkl, Kerstin, Schulz-Trieglaff, Elena Katharina, Klein, Rüdiger, Dudanova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549412/
https://www.ncbi.nlm.nih.gov/pubmed/36225731
http://dx.doi.org/10.3389/fnins.2022.1022251