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Efficacy Differences of First-line EGFR-TKIs Alone vs in Combination with Chemotherapy in Advanced Lung Adenocarcinoma Patients with Sensitive EGFR Mutation and Concomitant Non-EGFR Genetic Alterations

BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor (EGFR) mutations are often associated with non-EGFR genetic alterations, which may be a reason for the poor efficacy of EGFR tyrosine kinase inhibitors (TKIs). Here we conducted this study to explore whether EGFR-TKIs combined with chemother...

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Detalles Bibliográficos
Autores principales: ZHANG, Guowei, CHENG, Ruirui, NIU, Yuanyuan, WANG, Huijuan, YAN, Xiangtao, ZHANG, Mina, ZHANG, Xiaojuan, YANG, Jinpo, WEI, Chunhua, MA, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549422/
https://www.ncbi.nlm.nih.gov/pubmed/36172729
http://dx.doi.org/10.3779/j.issn.1009-3419.2022.102.34