Distal Ionic Substrate–Catalyst Interactions Enable Long-Range Stereocontrol: Access to Remote Quaternary Stereocenters through a Desymmetrizing Suzuki–Miyaura Reaction

[Image: see text] Spatial distancing of a substrate’s reactive group and nonreactive catalyst-binding group from its pro-stereogenic element presents substantial hurdles in asymmetric catalysis. In this context, we report a desymmetrizing Suzuki–Miyaura reaction that establishes chirality at a remot...

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Detalles Bibliográficos
Autores principales: Lou, Yazhou, Wei, Junqiang, Li, Mingfeng, Zhu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549467/
https://www.ncbi.nlm.nih.gov/pubmed/34979078
http://dx.doi.org/10.1021/jacs.1c12345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549467/
https://www.ncbi.nlm.nih.gov/pubmed/34979078
http://dx.doi.org/10.1021/jacs.1c12345

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