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ISGylation of EMD promotes its interaction with PDHA to inhibit aerobic oxidation in lung adenocarcinoma

Abnormal nuclear structure caused by dysregulation of skeletal proteins is a common phenomenon in tumour cells. However, how skeletal proteins promote tumorigenesis remains uncovered. Here, we revealed the mechanism by which skeletal protein Emerin (EMD) promoted glucose metabolism to induce lung ad...

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Detalles Bibliográficos
Autores principales: Zhang, Congcong, Cui, Jiangtao, Cao, Leiqun, Tian, Xiaoting, Miao, Yayou, Wang, Yikun, Qiu, Shiyu, Guo, Wanxin, Ma, Lifang, Xia, Jinjing, Zhang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549505/
https://www.ncbi.nlm.nih.gov/pubmed/36071546
http://dx.doi.org/10.1111/jcmm.17536