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Therapeutic hypothermia alleviates myocardial ischaemia–reperfusion injury by inhibiting inflammation and fibrosis via the mediation of the SIRT3/NLRP3 signalling pathway

Therapeutic hypothermia (TH) may attenuate myocardial ischaemia–reperfusion injury, thereby improving outcomes in acute myocardial infarction. However, the specific mechanism by which TH alleviates MIRI has not been elucidated so far. In this study, 120 healthy male Sprague‐Dawley rats were randomly...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Lu, Yimei, Yu, Peng, Li, Zhangwang, Liu, Yang, Zhang, Jun, Tang, Xiaoyi, Yu, Shuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549509/
https://www.ncbi.nlm.nih.gov/pubmed/36036085
http://dx.doi.org/10.1111/jcmm.17523