Facile synthesis, crystal structure, biological evaluation, and molecular modeling studies of N-((4-acetyl phenyl) carbamothioyl) pivalamide as the multitarget-directed ligand

The crystal structure of N-((4-acetylphenyl)carbamothioyl)pivalamide (3) was synthesized by inert refluxing pivaloyl isothiocyanate (2) and 4-aminoacetophenone in dry acetone. The spectroscopic characterization ((1)H-NMR, (13)CNMR, FT-IR) and single crystal assays determined the structure of synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Saeed, Aamer, Ejaz, Syeda Abida, Khalid, Aqsa, Channar, Pervaiz Ali, Aziz, Mubashir, Wani, Tanveer A., Zargar, Seema, Hassan, Sidra, Ismail, Hammad, Khalid, Dania, Hashmi, Muhammad Zaffar, Hökelek, Tuncer, Aborode, Abdullahi Tunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549587/
https://www.ncbi.nlm.nih.gov/pubmed/36226116
http://dx.doi.org/10.3389/fchem.2022.992701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549587/
https://www.ncbi.nlm.nih.gov/pubmed/36226116
http://dx.doi.org/10.3389/fchem.2022.992701

Ejemplares similares