CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation

BACKGROUND: Chemokine CXC motif receptor 7 (CXCR7) is an atypical G protein-coupled receptor (GPCR) that signals in a biased fashion. CXCL12/CXCR7 biased signal has been reported to play crucial roles in multiple stages of colorectal cancer (CRC). However, the mechanism of CXCL12/CXCR7 biased signal...

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Detalles Bibliográficos
Autores principales: Si, Mahan, Song, Yujia, Wang, Xiaohui, Wang, Dong, Liu, Xiaohui, Qu, Xianjun, Song, Zhiyu, Yu, Xinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549625/
https://www.ncbi.nlm.nih.gov/pubmed/36210463
http://dx.doi.org/10.1186/s13578-022-00908-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549625/
https://www.ncbi.nlm.nih.gov/pubmed/36210463
http://dx.doi.org/10.1186/s13578-022-00908-1

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