Cargando…

CXCL13 chemokine is a novel player in multiple myeloma osteolytic microenvironment, M2 macrophage polarization, and tumor progression

BACKGROUND: We assessed the mechanism by which multiple myeloma (MM) shapes the bone marrow (BM) microenvironment and affects MΦ polarization. METHODS: In vivo xenograft model of BM-disseminated human myeloma, as well as analysis of MM cell lines, stromal components, and primary samples from patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Beider, Katia, Voevoda-Dimenshtein, Valeria, Zoabi, Ali, Rosenberg, Evgenia, Magen, Hila, Ostrovsky, Olga, Shimoni, Avichai, Weiss, Lola, Abraham, Michal, Peled, Amnon, Nagler, Arnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549634/
https://www.ncbi.nlm.nih.gov/pubmed/36217194
http://dx.doi.org/10.1186/s13045-022-01366-5