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Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis

BACKGROUND: Liver metastasis (LM) is a major obstacle to the prognosis of gastric cancer (GC) patients, but the molecular mechanism underlying gastric cancer liver metastasis (GC-LM) remains unknown. Exosomes have been identified as an important mediator of communication between tumor cells and the...

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Detalles Bibliográficos
Autores principales: Qiu, Shengkui, Xie, Li, Lu, Chen, Gu, Chao, Xia, Yiwen, Lv, Jialun, Xuan, Zhe, Fang, Lang, Yang, Jing, Zhang, Lu, Li, Zheng, Wang, Weizhi, Xu, Hao, Li, Bowen, Xu, Zekuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549645/
https://www.ncbi.nlm.nih.gov/pubmed/36217165
http://dx.doi.org/10.1186/s13046-022-02499-8