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Fat transplantation induces dermal adipose regeneration and reverses skin fibrosis through dedifferentiation and redifferentiation of adipocytes

BACKGROUND: Localized scleroderma causes cosmetic disfigurement, joint contractures, and other functional impairment, but no currently available medications can reverse the resulting skin lesions. Fat grafting is beneficial for reversing skin fibrosis; however, the mechanism by which adipose tissue...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Cai, Junrong, Zhang, Qian, Wen, Jiaqing, Liao, Yunjun, Lu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549649/
https://www.ncbi.nlm.nih.gov/pubmed/36210466
http://dx.doi.org/10.1186/s13287-022-03127-0