Blood donor biobank and HLA imputation as a resource for HLA homozygous cells for therapeutic and research use

BACKGROUND: Allogeneic therapeutic cells may be rejected if they express HLA alleles not found in the recipient. As finding cell donors with a full HLA match to a recipient requires vast donor pools, the use of HLA homozygous cells has been suggested as an alternative. HLA homozygous cells should be...

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Detalles Bibliográficos
Autores principales: Clancy, Jonna, Hyvärinen, Kati, Ritari, Jarmo, Wahlfors, Tiina, Partanen, Jukka, Koskela, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549658/
https://www.ncbi.nlm.nih.gov/pubmed/36210465
http://dx.doi.org/10.1186/s13287-022-03182-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549658/
https://www.ncbi.nlm.nih.gov/pubmed/36210465
http://dx.doi.org/10.1186/s13287-022-03182-7

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