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Blood donor biobank and HLA imputation as a resource for HLA homozygous cells for therapeutic and research use
BACKGROUND: Allogeneic therapeutic cells may be rejected if they express HLA alleles not found in the recipient. As finding cell donors with a full HLA match to a recipient requires vast donor pools, the use of HLA homozygous cells has been suggested as an alternative. HLA homozygous cells should be...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549658/ https://www.ncbi.nlm.nih.gov/pubmed/36210465 http://dx.doi.org/10.1186/s13287-022-03182-7 |