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Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity
Fn14 is a cell surface receptor with key functions in tissue homeostasis and injury but is also linked to chronic diseases. Despite its physiological and medical importance, the regulation of Fn14 signaling and turnover is only partly understood. Here, we demonstrate that Fn14 is cleaved within its...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549706/ https://www.ncbi.nlm.nih.gov/pubmed/36069059 http://dx.doi.org/10.15252/emmm.202216084 |