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LIGHTHOUSE illuminates therapeutics for a variety of diseases including COVID-19

One of the bottlenecks in the application of basic research findings to patients is the enormous cost, time, and effort required for high-throughput screening of potential drugs for given therapeutic targets. Here we have developed LIGHTHOUSE, a graph-based deep learning approach for discovery of th...

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Detalles Bibliográficos
Autores principales: Shimizu, Hideyuki, Kodama, Manabu, Matsumoto, Masaki, Orba, Yasuko, Sasaki, Michihito, Sato, Akihiko, Sawa, Hirofumi, Nakayama, Keiichi I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549714/
https://www.ncbi.nlm.nih.gov/pubmed/36246574
http://dx.doi.org/10.1016/j.isci.2022.105314