Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S) binds to angiotensin-converting enzyme 2 (ACE2) to mediate membrane fusion via two distinct pathways: 1) a surface, serine protease-dependent or 2) an endosomal, cysteine protease-dependent pathway. In this study...

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Detalles Bibliográficos
Autores principales: Benlarbi, Mehdi, Laroche, Geneviève, Fink, Corby, Fu, Kathy, Mulloy, Rory P., Phan, Alexandra, Ariana, Ardeshir, Stewart, Corina M., Prévost, Jérémie, Beaudoin-Bussières, Guillaume, Daniel, Redaet, Bo, Yuxia, El Ferri, Omar, Yockell-Lelièvre, Julien, Stanford, William L., Giguère, Patrick M., Mubareka, Samira, Finzi, Andrés, Dekaban, Gregory A., Dikeakos, Jimmy D., Côté, Marceline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549715/
https://www.ncbi.nlm.nih.gov/pubmed/36254158
http://dx.doi.org/10.1016/j.isci.2022.105316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549715/
https://www.ncbi.nlm.nih.gov/pubmed/36254158
http://dx.doi.org/10.1016/j.isci.2022.105316

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