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The Fractalkine‐CX3CR1 Axis Regulates Non‐inflammatory Osteoclastogenesis by Enhancing Precursor Cell Survival

The chemokine fractalkine (FKN) is produced by various cell types, including osteoblasts and endothelial cells in bone tissue, and signals through a sole receptor, CX3CR1, which is expressed on monocytes/macrophages, including osteoclast precursors (OCPs). However, the direct effects of FKN signalin...

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Detalles Bibliográficos
Autores principales: Kuboi, Yoshikazu, Kuroda, Yukiko, Ohkuro, Masayoshi, Motoi, Sotaro, Tomimori, Yoshiya, Yasuda, Hisataka, Yasuda, Nobuyuki, Imai, Toshio, Matsuo, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549724/
https://www.ncbi.nlm.nih.gov/pubmed/36248274
http://dx.doi.org/10.1002/jbm4.10680