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In vitro activity of lactone ketolide nafithromycin (WCK 4873) against Streptococcus pneumoniae isolates enriched with macrolide-resistance phenotype collected from mainland China

BACKGROUND: Widespread MDR Streptococcus pneumoniae in China translates clinically into a substantial pneumococcal disease burden and related morbidity and mortality, particularly in the elderly and children. Nafithromycin (WCK 4873), a novel lactone ketolide class of antibiotic designed with a 3 da...

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Detalles Bibliográficos
Autores principales: Zhou, Menglan, Wu, Lijuan, Kang, Wei, Li, Yanbing, Zhang, Ge, Zhang, Jingjia, Duan, Simeng, Li, Jin, Wang, Tong, Xu, Yingchun, Gu, Yihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549737/
https://www.ncbi.nlm.nih.gov/pubmed/36226226
http://dx.doi.org/10.1093/jacamr/dlac103