Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm

A major complication in COVID-19 infection consists in the onset of acute respiratory distress fueled by a dysregulation of the host immune network that leads to a run-away cytokine storm. Here, we present an in silico approach that captures the host immune system’s complex regulatory dynamics, allo...

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Detalles Bibliográficos
Autores principales: Richman, Spencer, Lyman, Cole, Nesterova, Anastasia, Yuryev, Anton, Morris, Matthew, Cao, Hongbao, Cheadle, Chris, Skuse, Gary, Broderick, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549818/
https://www.ncbi.nlm.nih.gov/pubmed/36216820
http://dx.doi.org/10.1038/s41540-022-00250-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549818/
https://www.ncbi.nlm.nih.gov/pubmed/36216820
http://dx.doi.org/10.1038/s41540-022-00250-9

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