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Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm
A major complication in COVID-19 infection consists in the onset of acute respiratory distress fueled by a dysregulation of the host immune network that leads to a run-away cytokine storm. Here, we present an in silico approach that captures the host immune system’s complex regulatory dynamics, allo...
Autores principales: | Richman, Spencer, Lyman, Cole, Nesterova, Anastasia, Yuryev, Anton, Morris, Matthew, Cao, Hongbao, Cheadle, Chris, Skuse, Gary, Broderick, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549818/ https://www.ncbi.nlm.nih.gov/pubmed/36216820 http://dx.doi.org/10.1038/s41540-022-00250-9 |
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