Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers

PURPOSE: The purpose of this study is to investigate the effect of sildenafil a CYP3A4 substrate and inhibitor on the pharmacokinetics and safety of saxagliptin. METHODS: Eighteen healthy volunteers were recruited in sequential; single-center study to determine pharmacokinetic parameters of saxaglip...

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Detalles Bibliográficos
Autores principales: Mansour, Rania Y., ElBorolossy, Radwa, Shaheen, Sara M., Sabri, Nagwa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549831/
https://www.ncbi.nlm.nih.gov/pubmed/36214883
http://dx.doi.org/10.1007/s00228-022-03397-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549831/
https://www.ncbi.nlm.nih.gov/pubmed/36214883
http://dx.doi.org/10.1007/s00228-022-03397-w

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