Safety and immunogenicity of the Na-APR-1 hookworm vaccine in infection-naïve adults

BACKGROUND: The Necator americanus hemoglobinase, aspartic protease-1 (Na-APR-1), facilitates the ability of adult hookworms to parasitize the intestine of their human hosts. A recombinant version of APR-1 protected laboratory animals against hookworm infection by inducing neutralizing antibodies th...

Descripción completa

Detalles Bibliográficos
Autores principales: Diemert, David J., Zumer, Maria, Campbell, Doreen, Grahek, Shannon, Li, Guangzhao, Peng, Jin, Elena Bottazzi, Maria, Hotez, Peter, Bethony, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549940/
https://www.ncbi.nlm.nih.gov/pubmed/36114129
http://dx.doi.org/10.1016/j.vaccine.2022.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549940/
https://www.ncbi.nlm.nih.gov/pubmed/36114129
http://dx.doi.org/10.1016/j.vaccine.2022.09.017

Ejemplares similares