CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production

Chimeric antigen receptor (CAR)-T cells are engineered to identify and eliminate cells expressing a target antigen. Current manufacturing protocols vary between commercial CAR-T cell products warranting an assessment of these methods to determine which approach optimally balances successful manufact...

Descripción completa

Detalles Bibliográficos
Autores principales: Abraham-Miranda, Julieta, Menges, Meghan, Atkins, Reginald, Mattie, Mike, Kanska, Justyna, Turner, Joel, Hidalgo-Vargas, Melanie J., Locke, Frederick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549966/
https://www.ncbi.nlm.nih.gov/pubmed/36225930
http://dx.doi.org/10.3389/fimmu.2022.1007042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549966/
https://www.ncbi.nlm.nih.gov/pubmed/36225930
http://dx.doi.org/10.3389/fimmu.2022.1007042

Ejemplares similares