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CAR-T manufactured from frozen PBMC yield efficient function with prolonged in vitro production
Chimeric antigen receptor (CAR)-T cells are engineered to identify and eliminate cells expressing a target antigen. Current manufacturing protocols vary between commercial CAR-T cell products warranting an assessment of these methods to determine which approach optimally balances successful manufact...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9549966/ https://www.ncbi.nlm.nih.gov/pubmed/36225930 http://dx.doi.org/10.3389/fimmu.2022.1007042 |