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Towards reliable quantification of cell state velocities

A few years ago, it was proposed to use the simultaneous quantification of unspliced and spliced messenger RNA (mRNA) to add a temporal dimension to high-throughput snapshots of single cell RNA sequencing data. This concept can yield additional insight into the transcriptional dynamics of the biolog...

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Detalles Bibliográficos
Autores principales: Marot-Lassauzaie, Valérie, Bouman, Brigitte Joanne, Donaghy, Fearghal Declan, Demerdash, Yasmin, Essers, Marieke Alida Gertruda, Haghverdi, Laleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550177/
https://www.ncbi.nlm.nih.gov/pubmed/36170235
http://dx.doi.org/10.1371/journal.pcbi.1010031