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GSK3β-dependent lysosome biogenesis: An effective pathway to mitigate renal fibrosis with LM49
Renal fibrosis is an incurable disorder characterised by an imbalance of the extracellular matrix (ECM) favouring excess production over degradation. The identification of actionable pathways and agents that promote ECM degradation to restore ECM homeostasis may help mitigate renal fibrosis. In this...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550195/ https://www.ncbi.nlm.nih.gov/pubmed/36225562 http://dx.doi.org/10.3389/fphar.2022.925489 |