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GSK3β-dependent lysosome biogenesis: An effective pathway to mitigate renal fibrosis with LM49

Renal fibrosis is an incurable disorder characterised by an imbalance of the extracellular matrix (ECM) favouring excess production over degradation. The identification of actionable pathways and agents that promote ECM degradation to restore ECM homeostasis may help mitigate renal fibrosis. In this...

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Detalles Bibliográficos
Autores principales: Ren, Jinhong, Wei, Huizhi, Sun, Jian, Feng, Xiue, Zhang, Yuanlin, Yuan, Hongxia, Miao, Junqiu, Qi, Xiaoming, Qiao, Yuanbiao, Xiao, Baoguo, Li, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550195/
https://www.ncbi.nlm.nih.gov/pubmed/36225562
http://dx.doi.org/10.3389/fphar.2022.925489