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N-myc downstream regulated gene 1 (ndrg1) functions as a molecular switch for cellular adaptation to hypoxia

Lack of oxygen (hypoxia and anoxia) is detrimental to cell function and survival and underlies many disease conditions. Hence, metazoans have evolved mechanisms to adapt to low oxygen. One such mechanism, metabolic suppression, decreases the cellular demand for oxygen by downregulating ATP-demanding...

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Detalles Bibliográficos
Autores principales: Park, Jong S, Gabel, Austin M, Kassir, Polina, Kang, Lois, Chowdhary, Prableen K, Osei-Ntansah, Afia, Tran, Neil D, Viswanathan, Soujanya, Canales, Bryanna, Ding, Pengfei, Lee, Young-Sam, Brewster, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550225/
https://www.ncbi.nlm.nih.gov/pubmed/36214665
http://dx.doi.org/10.7554/eLife.74031