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A syngeneic MC38 orthotopic mouse model of colorectal cancer metastasis
While subcutaneous tumor models remain the standard for studying drug efficacy in vivo, these tumors rarely metastasize and lack physiological relevance due to differences in the tumor microenvironment, vascularization, immune landscape, and physiological cues associated with the organ of interest....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550231/ https://www.ncbi.nlm.nih.gov/pubmed/36225595 http://dx.doi.org/10.1093/biomethods/bpac024 |