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A syngeneic MC38 orthotopic mouse model of colorectal cancer metastasis

While subcutaneous tumor models remain the standard for studying drug efficacy in vivo, these tumors rarely metastasize and lack physiological relevance due to differences in the tumor microenvironment, vascularization, immune landscape, and physiological cues associated with the organ of interest....

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Detalles Bibliográficos
Autores principales: Greenlee, Joshua D, King, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550231/
https://www.ncbi.nlm.nih.gov/pubmed/36225595
http://dx.doi.org/10.1093/biomethods/bpac024