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Impact of cytotoxic agents or apoptosis stimulants on αklotho in MDCK, NRK-52E and HK2 kidney cells

αKlotho is a transmembrane protein acting as a co-receptor for FGF23, a bone hormone regulating renal phosphate and vitamin D metabolism. αKlotho expression is controlled by PPARγ. Soluble αklotho (sKL) regulates cellular signaling impacting stress resistance and death. αKlotho deficiency causes ear...

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Detalles Bibliográficos
Autores principales: Münz, Sina, Wolf, Lisa, Hoelzle, Ludwig E., Chernyakov, Dmitry, Edemir, Bayram, Föller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550246/
https://www.ncbi.nlm.nih.gov/pubmed/35997650
http://dx.doi.org/10.18632/aging.204238